Electrolytes & Kidney · HC-038

2021 CKD-EPI Creatinine eGFR Calculator (Adults)

Estimated glomerular filtration rate (eGFR) approximates kidney filtration using serum creatinine, age and the equation’s sex coefficient. The 2021 CKD-EPI equation does not use a race adjustment.

Enter your values

Calculations run in your browser. No inputs are sent to our server.

Result

Enter your values and select Calculate to see the result and an explanation.

Educational support only. Results are not medical advice and cannot replace professional assessment or your institution's protocols.

How the calculation works

The NIDDK 2021 CKD-EPI creatinine equation is 142 × min(SCr/κ,1)^α × max(SCr/κ,1)^−1.200 × 0.9938^age × 1.012 if female, where κ and α are sex-specific constants.

Worked example

For a 50-year-old man with serum creatinine of 1.0 mg/dL, eGFR is approximately 92 mL/min/1.73 m².

Understanding the result

This calculation is intended for adults and assumes creatinine values are appropriately standardized. It is not interchangeable with Cockcroft–Gault creatinine clearance for every drug-dosing decision.

Kidney disease evaluation considers persistence over time, urine albumin, clinical presentation and other data. Rapidly changing creatinine can make creatinine-based eGFR unreliable.

Limitations

For adults 18 years or older. Pediatric equations differ; a single eGFR estimate does not diagnose chronic kidney disease.